Wales skills coach Neil Jenkins says Wales cannot rely on Scotland or Italy to help them win the 2019 Six Nations if they lose to England in Cardiff next weekend.
The match next week is being labelled as a potential title decider.
Jenkins says the reality is that if they lose, they will be playing for second place.
England and Wales are the only two unbeaten teams left in the competition.
Wales will play England at 4.45am next Sunday.
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