Liverpool playmaker Philippe Coutinho is set to return after nearly seven weeks out with an ankle injury in the first leg of the English Football League Cup semi‑final.
Captain Jordan Henderson misses out due to injury.
Southampton will be without captain Jose Fonte as he put in a transfer request last week.
Liverpool will take on Southampton in the first leg of the English Football League Cup semi‑final at 8.45am today.
Meanwhile, Liverpool will face Manchester United in the English Premier League at 4am Monday.